Jujube is not only a favorite fruit, but also a good medicine to nourish the spleen and stomach, nourish the blood and calm the mind, and cure diseases and strengthen the body. In spring and autumn, when it is cold and warm at first, adding a few mulberry leaves to the jujube decoction as tea can prevent cold and flu; in summer, jujube and lotus leaves can be cooked together to reduce summer heat; in winter, jujube soup with ginger and brown sugar can drive away the cold and warm the stomach. In addition, red dates have the following effects: beauty, liver protection, prevent hair fall, nourish the blood, promote sleep, and prevent cardiovascular diseases.We
n 1979 and 1984, two Japanese scientists discovered that China's jujube fruit is rich in cAMP, which is tens of thousands of times the content of general animal and plant materials. The extraction has led to a new direction.
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What is cAMP?
Cyclic adenosine monophosphate (cAMP) is an important intracellular substance involved in the regulation of material metabolism and biological functions, and is the "second messenger" of life information transmission.
In vivo, it can promote the survival of cardiomyocytes, enhance the ability of cardiomyocytes to resist injury, ischemia and hypoxia; promote the flow of calcium ions to the cardiomyocytes, enhance the role of phosphorylation, and promote excitation-contraction coupling to improve the contraction force of the cardiomyocytes, increase the cardiac output; and at the same time, it can also dilate peripheral vasculature, reduce the ejection impedance of the heart, alleviate the anterior and posterior load on the heart, increase cardiac output, and improve the function of the heart. Thus, it plays the role of nutritive myocardium, positive inotropy, vasodilatation, anti-platelet aggregation and anti-arrhythmia to the heart.
It is mainly used for the treatment of cardiac insufficiency, angina pectoris and myocardial infarction in clinic. Especially for patients who are poisoned or insensitive to cardiotonic drugs of the class of Digitalis purpurea L.Digitalis purpurea L.. Cyclophosphoadenosine that enters cells is inactivated by phosphodiesterase degradation to 5-adenosine-5′-phosphate (5-AMP) after exerting its biological effect, which is then broken down into adenosine and phosphate. It is a protein kinase inactivator and a derivative of nucleotides. It is a physiologically active and important substance widely found in the human body, generated by adenosine triphosphate catalysed by adenylyl cyclase, which regulates a wide range of cellular functional activities.
As the second messenger of hormone, it plays the role of hormone regulation of physiological functions and material metabolism in cells, can change the function of cell membrane, prompt calcium ions in reticulocyte myoplasm to enter myofibres, thus enhancing myocardial contraction, and can promote the activity of respiratory chain oxidase, improve myocardial hypoxia, alleviate the symptoms of coronary artery disease and improve electrocardiogram.
In addition, it plays an important role in the regulation of sugar and fat metabolism, nucleic acid and protein synthesis.
Function of cAMP
*Improve endurance
1. cAMP promotes water reabsorption and reduces water loss during exercise.
2. cAMP increases myocardial contractility and increases heart rate.
3. cAMP can maximize glucose in muscle cells.
*Anti-aging
cAMP improves metabolic function and slows the aging process by regulating key proteins in metabolism and aging.
*Anti-tumor effects and cancer immunotherapy
1.cAMP can inhibit the proliferation of deteriorating cells and convert them to the normal direction.
2.cAMP has the effect of increasing leukocytes and can resist the reduction of normal leukocytes caused by radiotherapy and chemotherapy.
*Improve cardiovascular function
cAMP enables Ca in the sarcoplasmic reticulum to enter muscle fibers, thereby enhancing myocardial contractility, increasing cardiac output, and dilating coronary arteries.
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