| Berberine |
| Product Code | C110103 | Specification | Berberine 98% |
| Extract Source | Phellodendron Chinense | Part Used | Bark |
| Extract Solvent | Ethanol / Water | Assay Method | HPLC |
| CAS NO. | 2086-83-1 | Molecular Formula | C20H18NO4 |
| EINECS No. | 218-229-1 | Molecular Weight | 336.36 |
| Character | Light Yellow to Yellow | Certification | ISO22000 |
| HS Code | 3006930000 | Shelf Life | 2 Years |

Berberine, also known as berberine, is a quaternary ammonium alkaloid isolated from the traditional Chinese medicine Huanglian, which is the main active ingredient of Huanglian antimicrobial. It is yellow needle-like crystal with bitter taste. It is widely distributed in the plant kingdom, with berberine found in about 10 genera of 4 families.
It is 5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolane[5,6-α]quinolizine hydrochloride dihydrate. Properties This product is yellow crystalline powder; odorless, taste very bitter. It is soluble in hot water, slightly soluble in water or ethanol, very slightly soluble in trichloromethane, insoluble in ether.
Pharmacological action of antibacterial spectrum, in vitro on a variety of gram-positive and negative bacteria have bacteriostatic effect, including hemolytic streptococcus, aureus, Vibrio cholerae. Meningococcus, Shigella dysentery bacillus, typhoid fever bacillus, diphtheria bacillus, etc. It has strong inhibitory effect in low concentration and bactericidal effect in high concentration. It also has a certain inhibitory effect on influenza virus, amoeba, leptospirosis, and certain skin fungi. In vitro experiments have confirmed that safranin can enhance the phagocytosis of leukocytes and hepatic reticuloendothelial system. Dysentery bacillus, hemolytic streptococcus, aureus and so on are very easy to produce drug resistance to this product. There is no cross-resistance with penicillin and streptomycin.
Berberine also has an effect on Helicobacter, while it can reduce gastritis, gastric and duodenal ulcers. Indications It is mainly effective in the treatment of gastroenteritis, bacillary dysentery and other intestinal infections, ocular conjunctivitis, purulent otitis media. Recently, it has also been found to have blocked α-receptors and anti-arrhythmic effects.
Application of Berberine
Food, Health Care, Daily Necessities, Cosmetics, Functional Drink.
Package Of Berberine

Food Application

FAQ

Q1: What's the difference between herb extract and powder?
A: The extract is a concentrated powder form of raw material. The herb extract's procedure flow is wash, extraction, concentration, purification, drying, grinding, sieving, package. The herb powder is just a powder form of the herb. The procedure flow is wash, drying, grinding, sieving, package.
Q2: What's the extract solvent used in the procedure?
A: The extract solvent is always depending on the active ingredient in the raw material, regulation and customers' requirement. The solvents mostly used for extraction are water and ethanol. Even the solvent other than water used in the procedure, the solvent residue in the extract product also can conform with ICH Q3CR5.
Q3: Is there any other ingredient used in the product?
A: It depends. For product which is hard to be dried, we need to add some maltodextrin into the extraction solution before drying. The maltodextrin we used is food-class carrier, from non-GMO corn. We can share customer with the ingredient composition table.
Q4: How to make sure the quality of the product?
A: Firstly, every batch finish product must be tested and qualified before delivery. We can send a specification sheet or CoA for confirmation. The HPLC chromatography graph also can be provided. Secondly, we can provide pre-ship sample to customer for quality confirmation.
Q5: Can you develop a new product for us?
A: Yes, we can. We have independent R&D dept, who is able to update the procedure parameters of our main products and develop the procedure of new product. For more information, please contact us directly.
Q6: Can you offer this in capsules or tablets as well?
A: Yes, we have related equipment for preparation of finish product, like tablet, capsule and granule. Kindly contact with us for details.
Q7: What is the MOQ?
A: For most of the products we already have in stock, the MOQ is 1kg. If the product is a new specification and need to be produced from raw material, the MOQ depends.
Q8: Is there any discount?
A: Yes, for larger quantity or better payment period, we can support with better price.
Q9: How about delivery time?
A: For most products, the product can be sent out from factory in 5days. If we don't have inventory, the product need to produced from raw material, the ordinary period is 20-25days.
Q10: How do you treat with quality complaint?
A: We will always be responsible for the quality of our products. If there's a complaint, we will first assist customers to solve the most direct needs.
Secondly, we have SOP for quality complaint. QA will investigate the problem, after that we'll give customer a formal feedback about the cause of the quality issue and related precautions for this problem.
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