Melatonin |
Specification | Purity over 99.5%, Peak E free. | Molecular formula | C13H16N2O2 |
CAS No. | 73-31-4 | EINECS | 200-797-7 |
Assay Method | HPLC;IR;UV | Character | Off-white to White |
HS Code | 1302199099 | Certification | ISO22000 |
Solubility | soluble in ethanol, acid, alkali and brine. solubility of ethanol at 25℃ is about 14g/100g; solubility of ethylene glycol at 25℃ is 7g/100g. |
Alias | N-Acetyl-5-ethoxytrptamine, alias N-[2-(5-methoxy-3-indolyl)ethyl]acetamide, pinealectin |
Introduction of Melatonin
Melatonin (MT) is one of the hormones secreted by the pineal gland of the brain. Melatonin belongs to the indole heterocyclic group of compounds whose chemical name is N-acetyl-5 methoxytryptamine, also known as pinealectin, melatonin, and melatonin. After melatonin synthesis, it is stored in the pineal gland, where sympathetic excitation innervates the pineal cells to release melatonin. Melatonin secretion has a distinct circadian rhythm, with daytime secretion inhibited and nighttime secretion active. Melatonin inhibits the hypothalamic-pituitary-gonadal axis, reducing the levels of gonadotropin-releasing hormone, gonadotropin, luteinizing hormone and follicular estrogen, and acting directly on the gonads to reduce the levels of androgens, estrogens and progesterone. In addition, MT has powerful neuroendocrine immunomodulatory activity and free radical scavenging antioxidant capacity, which may become a new method and avenue for antiviral therapy. MT is ultimately metabolized in the liver, and damage to hepatocytes can affect the level of MT in the body.
Function of Melatonin
· Improve Sleep Quality
· Protect cardiovascular and cerebrovascular
· Antioxidant
Specification of Melatonin
Application of Melatonin
Food, Health Care, Daily Necessities, Cosmetics, Functional Drink.
In health supplements, the most common application of melatonin is to promote sleep, reduce the time to fall asleep, increase the duration of sleep, but also to enhance the quality of sleep, so that people can more easily enter a deep sleep. It helps people to better relieve physical and psychological stress. Enhance the body's resistance.
Help the elderly to improve sleep quality and relieve some depressive symptoms in the elderly, while also helping to regulate the balance of the body's internal metabolism and prevent the occurrence of cardiovascular disease.
Food Application

FAQ

Q1: What's the difference between herb extract and powder?
A: The extract is a concentrated powder form of raw material. The herb extract's procedure flow is wash, extraction, concentration, purification, drying, grinding, sieving, package. The herb powder is just a powder form of the herb. The procedure flow is wash, drying, grinding, sieving, package.
Q2: What's the extract solvent used in the procedure?
A: The extract solvent is always depending on the active ingredient in the raw material, regulation and customers' requirement. The solvents mostly used for extraction are water and ethanol. Even the solvent other than water used in the procedure, the solvent residue in the extract product also can conform with ICH Q3CR5.
Q3: Is there any other ingredient used in the product?
A: It depends. For product which is hard to be dried, we need to add some maltodextrin into the extraction solution before drying. The maltodextrin we used is food-class carrier, from non-GMO corn. We can share customer with the ingredient composition table.
Q4: How to make sure the quality of the product?
A: Firstly, every batch finish product must be tested and qualified before delivery. We can send a specification sheet or CoA for confirmation. The HPLC chromatography graph also can be provided. Secondly, we can provide pre-ship sample to customer for quality confirmation.
Q5: Can you develop a new product for us?
A: Yes, we can. We have independent R&D dept, who is able to update the procedure parameters of our main products and develop the procedure of new product. For more information, please contact us directly.
Q6: Can you offer this in capsules or tablets as well?
A: Yes, we have related equipment for preparation of finish product, like tablet, capsule and granule. Kindly contact with us for details.
Q7: What is the MOQ?
A: For most of the products we already have in stock, the MOQ is 1kg. If the product is a new specification and need to be produced from raw material, the MOQ depends.
Q8: Is there any discount?
A: Yes, for larger quantity or better payment period, we can support with better price.
Q9: How about delivery time?
A: For most products, the product can be sent out from factory in 5days. If we don't have inventory, the product need to produced from raw material, the ordinary period is 20-25days.
Q10: How do you treat with quality complaint?
A: We will always be responsible for the quality of our products. If there's a complaint, we will first assist customers to solve the most direct needs.
Secondly, we have SOP for quality complaint. QA will investigate the problem, after that we'll give customer a formal feedback about the cause of the quality issue and related precautions for this problem.
Other recommendation