Resvertrol |
Product Code | C080701 | Specification | 50%-99% HPLC |
Synonyms | RES | Chemical formula | C14H1203 |
Molecular weight | 228.243 | CAS No. | 501-36-0 |
EINECS No. | 610-504-8 | Certification | ISO22000, KOSHER, HALAL |
Melting Point | 253 to 255 C | Shelf Life | 3 Years |
Resvertrol is a naturally occurring stilbene compound, a non-flavonoid polyphenol containing an astragaloid structure. It is present in a variety of plants such as grapes, pomegranates, thuja, and blueberries.
It is a natural active ingredient that can be distributed and biosynthesized in two forms: free (cis, trans) and sugar-bound (cis, trans) in plants (e.g., Chinese herbal medicine, thuja), and both have antioxidant efficacy, with the trans-isomer being more biologically active than the cis form, making it an important plant antitoxin in grapes.
Resveratrol is effective through targeting nuclear factor-κB (NF-κB), cell silencing binding protein 1 (Sirt1), cell silencing binding protein 3 (Sirt3), lactate dehydrogenase (LDH), phosphatidylinositol 3-kinase (PI3K), mammalian target of rapamycin (m TOR), and recombinant human M2-type pyruvate kinase (PKM2) to inhibit cancer cell growth, invasion, and proliferation. Resvertrol also induces apoptosis by activating oncogenes p53 and phosphatase tensin homolog (PTEN) and downregulating PI3K to arrest the cell cycle.
In addition, Resvertrol can activate immune cells in the tumor microenvironment, such as natural killer (NK) cells and CD8+ lymphocytes, enhance the activity of immune cells, cause the release of tumor necrosis factor-α (TNF-α) and thus induce apoptosis of cancer cells. In addition, compared with other anti-cancer drugs, Resveratrol not only enhances the sensitivity of cancer cells to radiotherapy, but also protects normal tissue cells.
The chemical formula of Resvertrol is C14H12O3, which is not easily soluble in water but in solvents such as ethanol and dimethyl sulfoxide. Resvertrol not only exhibits good anti-inflammatory, antioxidant, antiviral, hypolipidemic, hypoglycemic and anticancer properties, but also can be used as a supplement to play a preventive role in cardiovascular system diseases, neurological diseases and cancer.
Application of Resvertrol
Food, Health Care, Daily Necessities, Cosmetics, Functional Drink.
Process Flow Chart of Resvertrol

Food Application

FAQ

Q1: What's the difference between herb extract and powder?
A: The extract is a concentrated powder form of raw material. The herb extract's procedure flow is wash, extraction, concentration, purification, drying, grinding, sieving, package. The herb powder is just a powder form of the herb. The procedure flow is wash, drying, grinding, sieving, package.
Q2: What's the extract solvent used in the procedure?
A: The extract solvent is always depending on the active ingredient in the raw material, regulation and customers' requirement. The solvents mostly used for extraction are water and ethanol. Even the solvent other than water used in the procedure, the solvent residue in the extract product also can conform with ICH Q3CR5.
Q3: Is there any other ingredient used in the product?
A: It depends. For product which is hard to be dried, we need to add some maltodextrin into the extraction solution before drying. The maltodextrin we used is food-class carrier, from non-GMO corn. We can share customer with the ingredient composition table.
Q4: How to make sure the quality of the product?
A: Firstly, every batch finish product must be tested and qualified before delivery. We can send a specification sheet or CoA for confirmation. The HPLC chromatography graph also can be provided. Secondly, we can provide pre-ship sample to customer for quality confirmation.
Q5: Can you develop a new product for us?
A: Yes, we can. We have independent R&D dept, who is able to update the procedure parameters of our main products and develop the procedure of new product. For more information, please contact us directly.
Q6: Can you offer this in capsules or tablets as well?
A: Yes, we have related equipment for preparation of finish product, like tablet, capsule and granule. Kindly contact with us for details.
Q7: What is the MOQ?
A: For most of the products we already have in stock, the MOQ is 1kg. If the product is a new specification and need to be produced from raw material, the MOQ depends.
Q8: Is there any discount?
A: Yes, for larger quantity or better payment period, we can support with better price.
Q9: How about delivery time?
A: For most products, the product can be sent out from factory in 5days. If we don't have inventory, the product need to produced from raw material, the ordinary period is 20-25days.
Q10: How do you treat with quality complaint?
A: We will always be responsible for the quality of our products. If there's a complaint, we will first assist customers to solve the most direct needs.
Secondly, we have SOP for quality complaint. QA will investigate the problem, after that we'll give customer a formal feedback about the cause of the quality issue and related precautions for this problem.
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